{"schema_version":"alpha-profile-public-v1","slug":"regina-m-graul-ph-d","canonical_url":"https://registry.alpha.ac/people/regina-m-graul-ph-d","as_of":"2026-10-09T17:57:09.894881+00:00","published_at":"2026-09-02T02:37:22.412006+00:00","last_reviewed_at":"2026-05-16T01:18:35.287+00:00","identity":{"display_name":"Regina M. Graul, Ph.D.","headshot_url":null,"headshot_media":null,"profile_kind":"director","role_tags":["director","executive"],"current_role":{"company_name":"Cyclerion Therapeutics, Inc.","company_slug":"cyclerion-therapeutics-inc","exchange":"NASDAQ","ticker":"CYCN","role_category":"director","title":"Director","committee":null,"is_board_chair":false,"is_independent":false,"valid_from":"2024-01-01","valid_to":null,"is_current":true,"verification_status":"confirmed","confidence":0.85,"evidence":{"source_type":"sec_proxy","source_url":"https://www.sec.gov/Archives/edgar/data/1755237/000114036125016370/ny20045439x1_def14a.htm","effective_date":"2025-04-29","last_checked_at":"2026-04-28T23:38:01.917+00:00"}},"photo_match":null},"assurance":{"is_claimed":false,"status":"unverified","assurance_level":null,"method":null,"verified_at":null,"expires_at":null},"claiming":{"eligible":true,"label":"Is this you? Claim your Alpha Profile","claim_url":"https://terminal.alpha.ac/claim-profile?person=regina-m-graul-ph-d","suggest_edit_label":"Suggest an edit","suggest_edit_url":"https://terminal.alpha.ac/claim-profile?person=regina-m-graul-ph-d&mode=suggest","canonical_record_will_be_reused":true,"canonical_facts_owner_controlled":false},"presentation":{"schema_version":"alpha-profile-presentation-v1","state":"alpha_editorial","version":0,"published_at":null,"headline":null,"headline_evidence":null,"location":null,"photo":null,"cover":null,"about":["Dr. Graul brings extensive drug research and development experience in the biopharmaceutical industry over 21 years. She served as VP program executive at EQRx Therapeutics leading multiple portfolios, senior director at Cyclerion leading the olinciguat franchise, and held numerous roles at Ironwood Pharmaceuticals including head of internal innovation and senior director of R&D. She holds a Ph.D. in synthetic organic chemistry from Rice University."],"links":[],"sources":[],"featured":[],"competencies":[],"board_preferences":null,"board_service":[{"organization":"Cyclerion Therapeutics, Inc.","organizationId":"cyclerion-therapeutics-inc","title":"Director","period":"2024-01-01 · current","evidenceLabel":"sec_proxy","evidenceState":"verified","sourceUrl":"https://www.sec.gov/Archives/edgar/data/1755237/000114036125016370/ny20045439x1_def14a.htm"}],"experience":[],"education":[],"credentials":[],"section_order":null,"hidden_sections":[],"limitations":["Presentation fields do not alter independently verified Alpha Profile facts.","Owner-supplied résumé records retain their field-level evidence state.","Only confirmed company_person_roles with public evidence. Website governed_site_fallback rows are not invented. about/links are stored people.profile_summary/bio and linkedin_url only. Dates stay undisclosed when the role has no start_date. SoFi Bank is not SoFi Technologies."]},"presentation_authority":"confirmed_company_person_roles","roles":[{"company_name":"Cyclerion Therapeutics, Inc.","company_slug":"cyclerion-therapeutics-inc","exchange":"NASDAQ","ticker":"CYCN","role_category":"director","title":"Director","committee":null,"is_board_chair":false,"is_independent":false,"valid_from":"2024-01-01","valid_to":null,"is_current":true,"verification_status":"confirmed","confidence":0.85,"evidence":{"source_type":"sec_proxy","source_url":"https://www.sec.gov/Archives/edgar/data/1755237/000114036125016370/ny20045439x1_def14a.htm","effective_date":"2025-04-29","last_checked_at":"2026-04-28T23:38:01.917+00:00"}}],"claims":[{"claim_type":"ai_ml_experience","claim_value":false,"claim_text":"Proxy extraction classified AI/ML experience for Regina M. Graul, Ph.D. as false.","claim_state":"verified","valid_from":null,"valid_to":null,"confidence":0.72,"source_tier":3,"verification_status":"confirmed","last_reviewed_at":"2026-05-15T23:10:40.345561+00:00","version":1,"evidence":[{"source_name":"SEC EDGAR","document_title":"CYCN DEF 14A director slate","source_type":"sec_filing","source_tier":3,"source_url":"https://www.sec.gov/Archives/edgar/data/1755237/000114036125016370/ny20045439x1_def14a.htm","published_at":"2025-04-29T00:00:00+00:00","last_checked_at":"2026-05-15T23:10:40.233892+00:00","relation":"supports","excerpt_locator":null}]},{"claim_type":"ai_ml_experience","claim_value":false,"claim_text":"Executive extraction classified AI/ML experience for Regina M. Graul, Ph.D. as false.","claim_state":"verified","valid_from":null,"valid_to":null,"confidence":0.72,"source_tier":3,"verification_status":"confirmed","last_reviewed_at":"2026-05-16T01:18:35.541136+00:00","version":1,"evidence":[{"source_name":"SEC EDGAR","document_title":"CYCN DEF 14A executive officers","source_type":"sec_filing","source_tier":3,"source_url":"https://www.sec.gov/Archives/edgar/data/1755237/000114036125016370/ny20045439x1_def14a.htm","published_at":"2025-04-29T00:00:00+00:00","last_checked_at":"2026-05-16T01:18:35.37173+00:00","relation":"supports","excerpt_locator":null}]},{"claim_type":"board_role","claim_value":"Director","claim_text":"Regina M. Graul, Ph.D. currently serves as Director at Cyclerion Therapeutics, Inc..","claim_state":"verified","valid_from":"2025-04-29","valid_to":null,"confidence":0.92,"source_tier":3,"verification_status":"confirmed","last_reviewed_at":"2026-05-15T23:10:40.30653+00:00","version":1,"evidence":[{"source_name":"SEC EDGAR","document_title":"CYCN DEF 14A director slate","source_type":"sec_filing","source_tier":3,"source_url":"https://www.sec.gov/Archives/edgar/data/1755237/000114036125016370/ny20045439x1_def14a.htm","published_at":"2025-04-29T00:00:00+00:00","last_checked_at":"2026-05-15T23:10:40.233892+00:00","relation":"supports","excerpt_locator":null}]},{"claim_type":"committee_assignments","claim_value":[],"claim_text":"Regina M. Graul, Ph.D. serves on no disclosed committees.","claim_state":"verified","valid_from":"2025-04-29","valid_to":null,"confidence":0.88,"source_tier":3,"verification_status":"confirmed","last_reviewed_at":"2026-05-15T23:10:40.322643+00:00","version":1,"evidence":[{"source_name":"SEC EDGAR","document_title":"CYCN DEF 14A director slate","source_type":"sec_filing","source_tier":3,"source_url":"https://www.sec.gov/Archives/edgar/data/1755237/000114036125016370/ny20045439x1_def14a.htm","published_at":"2025-04-29T00:00:00+00:00","last_checked_at":"2026-05-15T23:10:40.233892+00:00","relation":"supports","excerpt_locator":null}]},{"claim_type":"current_executive_company","claim_value":"Cyclerion Therapeutics, Inc.","claim_text":"Regina M. Graul, Ph.D. is linked to Cyclerion Therapeutics, Inc. as an operating executive.","claim_state":"verified","valid_from":null,"valid_to":null,"confidence":0.85,"source_tier":3,"verification_status":"confirmed","last_reviewed_at":"2026-05-15T23:10:40.460096+00:00","version":1,"evidence":[{"source_name":"SEC EDGAR","document_title":"CYCN DEF 14A director slate","source_type":"sec_filing","source_tier":3,"source_url":"https://www.sec.gov/Archives/edgar/data/1755237/000114036125016370/ny20045439x1_def14a.htm","published_at":"2025-04-29T00:00:00+00:00","last_checked_at":"2026-05-15T23:10:40.233892+00:00","relation":"supports","excerpt_locator":null}]},{"claim_type":"current_executive_role","claim_value":"President and Chief Executive Officer","claim_text":"Regina M. Graul, Ph.D. is also listed as President and Chief Executive Officer.","claim_state":"verified","valid_from":null,"valid_to":null,"confidence":0.85,"source_tier":3,"verification_status":"confirmed","last_reviewed_at":"2026-05-15T23:10:40.444264+00:00","version":1,"evidence":[{"source_name":"SEC EDGAR","document_title":"CYCN DEF 14A director slate","source_type":"sec_filing","source_tier":3,"source_url":"https://www.sec.gov/Archives/edgar/data/1755237/000114036125016370/ny20045439x1_def14a.htm","published_at":"2025-04-29T00:00:00+00:00","last_checked_at":"2026-05-15T23:10:40.233892+00:00","relation":"supports","excerpt_locator":null}]},{"claim_type":"cybersecurity_experience","claim_value":false,"claim_text":"Proxy extraction classified cybersecurity experience for Regina M. Graul, Ph.D. as false.","claim_state":"verified","valid_from":null,"valid_to":null,"confidence":0.72,"source_tier":3,"verification_status":"confirmed","last_reviewed_at":"2026-05-15T23:10:40.39969+00:00","version":1,"evidence":[{"source_name":"SEC EDGAR","document_title":"CYCN DEF 14A director slate","source_type":"sec_filing","source_tier":3,"source_url":"https://www.sec.gov/Archives/edgar/data/1755237/000114036125016370/ny20045439x1_def14a.htm","published_at":"2025-04-29T00:00:00+00:00","last_checked_at":"2026-05-15T23:10:40.233892+00:00","relation":"supports","excerpt_locator":null}]},{"claim_type":"cybersecurity_experience","claim_value":false,"claim_text":"Executive extraction classified cybersecurity experience for Regina M. Graul, Ph.D. as false.","claim_state":"verified","valid_from":null,"valid_to":null,"confidence":0.72,"source_tier":3,"verification_status":"confirmed","last_reviewed_at":"2026-05-16T01:18:35.583475+00:00","version":1,"evidence":[{"source_name":"SEC EDGAR","document_title":"CYCN DEF 14A executive officers","source_type":"sec_filing","source_tier":3,"source_url":"https://www.sec.gov/Archives/edgar/data/1755237/000114036125016370/ny20045439x1_def14a.htm","published_at":"2025-04-29T00:00:00+00:00","last_checked_at":"2026-05-16T01:18:35.37173+00:00","relation":"supports","excerpt_locator":null}]},{"claim_type":"executive_company","claim_value":"Cyclerion Therapeutics, Inc.","claim_text":"Regina M. Graul, Ph.D. is associated with Cyclerion Therapeutics, Inc..","claim_state":"verified","valid_from":"2025-04-29","valid_to":null,"confidence":0.94,"source_tier":3,"verification_status":"confirmed","last_reviewed_at":"2026-05-16T01:18:35.522542+00:00","version":1,"evidence":[{"source_name":"SEC EDGAR","document_title":"CYCN DEF 14A executive officers","source_type":"sec_filing","source_tier":3,"source_url":"https://www.sec.gov/Archives/edgar/data/1755237/000114036125016370/ny20045439x1_def14a.htm","published_at":"2025-04-29T00:00:00+00:00","last_checked_at":"2026-05-16T01:18:35.37173+00:00","relation":"supports","excerpt_locator":null}]},{"claim_type":"executive_title","claim_value":"President and Chief Executive Officer","claim_text":"Regina M. Graul, Ph.D. is listed as President and Chief Executive Officer at Cyclerion Therapeutics, Inc..","claim_state":"verified","valid_from":"2025-04-29","valid_to":null,"confidence":0.94,"source_tier":3,"verification_status":"confirmed","last_reviewed_at":"2026-05-16T01:18:35.499772+00:00","version":1,"evidence":[{"source_name":"SEC EDGAR","document_title":"CYCN DEF 14A executive officers","source_type":"sec_filing","source_tier":3,"source_url":"https://www.sec.gov/Archives/edgar/data/1755237/000114036125016370/ny20045439x1_def14a.htm","published_at":"2025-04-29T00:00:00+00:00","last_checked_at":"2026-05-16T01:18:35.37173+00:00","relation":"supports","excerpt_locator":null}]},{"claim_type":"technology_background","claim_value":false,"claim_text":"Proxy extraction classified technology background for Regina M. Graul, Ph.D. as false.","claim_state":"verified","valid_from":null,"valid_to":null,"confidence":0.72,"source_tier":3,"verification_status":"confirmed","last_reviewed_at":"2026-05-15T23:10:40.362031+00:00","version":1,"evidence":[{"source_name":"SEC EDGAR","document_title":"CYCN DEF 14A director slate","source_type":"sec_filing","source_tier":3,"source_url":"https://www.sec.gov/Archives/edgar/data/1755237/000114036125016370/ny20045439x1_def14a.htm","published_at":"2025-04-29T00:00:00+00:00","last_checked_at":"2026-05-15T23:10:40.233892+00:00","relation":"supports","excerpt_locator":null}]},{"claim_type":"technology_background","claim_value":false,"claim_text":"Executive extraction classified technology background for Regina M. Graul, Ph.D. as false.","claim_state":"verified","valid_from":null,"valid_to":null,"confidence":0.72,"source_tier":3,"verification_status":"confirmed","last_reviewed_at":"2026-05-16T01:18:35.564386+00:00","version":1,"evidence":[{"source_name":"SEC EDGAR","document_title":"CYCN DEF 14A executive officers","source_type":"sec_filing","source_tier":3,"source_url":"https://www.sec.gov/Archives/edgar/data/1755237/000114036125016370/ny20045439x1_def14a.htm","published_at":"2025-04-29T00:00:00+00:00","last_checked_at":"2026-05-16T01:18:35.37173+00:00","relation":"supports","excerpt_locator":null}]},{"subject":"alpha:person:regina-m-graul-ph-d","claim_type":"board_service","claim_value":{"tags":[],"title":"Director","period":"2024-01-01 · current","organization":"Cyclerion Therapeutics, Inc.","organization_id":"cyclerion-therapeutics-inc"},"claim_text":"Director at Cyclerion Therapeutics, Inc. (2024-01-01 · current)","valid_from":null,"valid_to":null,"verification_status":"confirmed","date_precision":"period_text_only","evidence":[{"source_url":"https://www.sec.gov/Archives/edgar/data/1755237/000114036125016370/ny20045439x1_def14a.htm","label":"sec_proxy","evidence_state":"verified"}],"claim_state":"confirmed","version":1}],"network":{"schema_version":"alpha-profile-network-public-v1","relationships":[],"relationship_pathfinding":false,"authentication_prompt":"Sign in to see how you're connected.","limitations":["Representative factual associations only.","Shared contexts do not assert personal acquaintance.","Anonymous graph traversal is not available."]},"permissions":{"classification":"open_public_projection","public_retrieval":true,"agent_retrieval":true,"redistribution":false,"model_training":false,"relationship_pathfinding":false,"direct_contact":false},"limitations":["Only permissioned public claims and evidence are included.","Absence of a claim is not evidence that the underlying fact is false.","Public retrieval does not grant model-training or redistribution rights.","Private relationships and Council activity are excluded."],"structured_data":{"@context":"https://schema.org","@type":"ProfilePage","@id":"https://registry.alpha.ac/people/regina-m-graul-ph-d#profile","url":"https://registry.alpha.ac/people/regina-m-graul-ph-d","dateModified":"2026-05-16T01:18:35.287+00:00","mainEntity":{"@type":"Person","@id":"https://registry.alpha.ac/people/regina-m-graul-ph-d#person","name":"Regina M. Graul, Ph.D.","url":"https://registry.alpha.ac/people/regina-m-graul-ph-d","jobTitle":"Director","worksFor":{"@type":"Organization","name":"Cyclerion Therapeutics, Inc.","tickerSymbol":"NASDAQ: CYCN"},"affiliation":[{"@type":"OrganizationRole","roleName":"Director","startDate":"2024-01-01","memberOf":{"@type":"Organization","name":"Cyclerion Therapeutics, Inc.","url":"https://registry.alpha.ac/companies/cyclerion-therapeutics-inc","tickerSymbol":"NASDAQ: CYCN"}}]},"isBasedOn":[{"@type":"CreativeWork","url":"https://www.sec.gov/Archives/edgar/data/1755237/000114036125016370/ny20045439x1_def14a.htm","name":"CYCN DEF 14A director slate"}],"mainEntityOfPage":"https://registry.alpha.ac/people/regina-m-graul-ph-d"},"registry_intelligence":{"schema_version":"alpha-registry-intelligence-v1","record_version":"d751713988987e9331980363e24189ce","subject":"alpha:person:regina-m-graul-ph-d","as_of":"2026-10-09T17:57:10.244151+00:00","recorded_at":"2026-10-09T17:57:10.244151+00:00","availability":"available","records":[],"next_offset":null,"limitations":["Only explicitly published, rights-cleared records. Missing records do not establish absence, safety, or complete coverage."]},"trust":{"schema_version":"alpha-profile-trust-v1","verification":{"schema_version":"alpha-verification-states-v1","state":"corroborated","identity_ownership":"unclaimed","assurance_level":null,"claim_state_counts":{"source_reported":4,"corroborated":5,"alpha_verified":0,"disputed":0,"superseded":0},"derivation":"claim_states+identity_ownership","summary":"At least one published claim is corroborated by two or more public sources. Profile ownership is unclaimed."},"aggregation":{"schema_version":"alpha-claim-aggregation-v1","published_claim_count":9,"under_review_claim_count":0,"owner_supplied_claim_count":0,"evidence_record_count":4,"distinct_source_count":1,"conflicts":[],"conflict_count":0,"headline_conflict_count":0,"internal_review_conflict_count":0,"contradiction_types":[],"headline_conflict_types":[],"verification":{"schema_version":"alpha-verification-states-v1","state":"corroborated","identity_ownership":"unclaimed","assurance_level":null,"claim_state_counts":{"source_reported":4,"corroborated":5,"alpha_verified":0,"disputed":0,"superseded":0},"derivation":"claim_states+identity_ownership","summary":"At least one published claim is corroborated by two or more public sources. Profile ownership is unclaimed."},"coverage":{"schema_version":"alpha-coverage-metric-v1","published_claims":9,"corroborated_claims":5,"sources":4,"distinct_sources":1,"role_claims":1,"last_reviewed_at":"2026-05-16T01:18:35.287+00:00","observed_at":"2026-10-09T17:57:09.894881+00:00","freshness_days":147}},"rights":{"public_retrieval":"allowed","agent_retrieval":"allowed","redistribution":"not_granted","model_training":"not_granted","commercial_use":"not_specified","relationship_pathfinding":"not_granted","direct_contact":"not_granted"}},"projection":{"schema_version":"alpha-profile-projection-v5","entity":{"kind":"person","slug":"regina-m-graul-ph-d","canonical_url":"https://registry.alpha.ac/people/regina-m-graul-ph-d"},"publication":{"published_at":"2026-09-02T02:37:22.412006+00:00","last_reviewed_at":"2026-05-16T01:18:35.287+00:00","as_of":"2026-10-09T17:57:09.894881+00:00"},"representations":{"html":{"href":"https://registry.alpha.ac/people/regina-m-graul-ph-d","media_type":"text/html"},"json":{"href":"https://registry.alpha.ac/api/public/profiles/regina-m-graul-ph-d","media_type":"application/json"},"markdown":{"href":"https://registry.alpha.ac/people/regina-m-graul-ph-d.md","media_type":"text/markdown"},"structured_data":{"embedded":true,"media_type":"application/ld+json"},"share_image":null},"permissions":{"public_retrieval":true,"agent_retrieval":true,"redistribution":false,"model_training":false,"relationship_pathfinding":false,"direct_contact":false}}}