# Cyclerion Therapeutics, Inc. > Alpha governed public record. Unknown, unavailable, and unpublished values are never inferred as zero. ## Record | Field | Value | | --- | --- | | Representation | alpha-profile-markdown-v4 | | Protocol | Alpha Governance Facts Protocol 0.1 | | Schema | alpha.governance.entity.public.v1 | | Record version | public-1:d751713988987e9331980363e24189ce:ro-d751713988987e9331980363e24189ce | | Governance record representation | alpha-governance-record-v2 | | Canonical entity | alpha:company:dc63c659-5918-479d-8f51-69ba8312563d | | Entity type | Company | | Canonical URL | https://registry.alpha.ac/companies/cyclerion-therapeutics-inc | | Publication | PUBLISHED | | Verification | source_reported | | Verification schema | alpha-verification-states-v1 | | Ownership | unclaimed | | Published claims | 16 | | Claims under review | 1 | | Evidence records | 5 | | Conflicts | 0 | | Conflicts in internal review | 0 | | Observed | 2026-10-09T04:48:32.027887+00:00 | | Last reviewed | 2026-10-09T04:48:32.027887+00:00 | ## Identity - Legal name: Cyclerion Therapeutics, Inc. - Display name: Cyclerion Therapeutics, Inc. ## Alpha Governance Record | Field | Value | | --- | --- | | Governance Record schema | alpha-governance-record-v2 | | Ontology | alpha-governance-ontology-v1 | | Record version | public-1:d751713988987e9331980363e24189ce:ro-d751713988987e9331980363e24189ce | | As of | 2026-10-09T17:11:23.052419+00:00 | | Completeness | 0.409 | | Record Quality | 0.841 | | Directors | 6 | | Committees | 3 | | Governance events | 10 | | Entity class | public_company | ## Section coverage | Section | State | | --- | --- | | identity | PUBLISHED | | corporate_structure | NOT_REVIEWED | | board | PUBLISHED | | committees | PUBLISHED | | leadership | PUBLISHED | | ownership | NOT_REVIEWED | | financials | NOT_REVIEWED | | capital_structure | PUBLISHED | | compensation | NOT_REVIEWED | | governance | NOT_REVIEWED | | shareholder_governance | NOT_REVIEWED | | audit | NOT_REVIEWED | | legal | NOT_REVIEWED | | risk | NOT_REVIEWED | | cyber | NOT_REVIEWED | | ai_governance | NOT_REVIEWED | | agent_governance | RESTRICTED | | markets_external | NOT_REVIEWED | | events | PUBLISHED | | relationships | PUBLISHED | | assessments | PUBLISHED | | evidence | PUBLISHED | ## Board - Dina Katabi, Ph.D.: Director. Status: current. Independent: true. Since: 2023-01-01. claim_id=alpha:claim:company:dc63c659-5918-479d-8f51-69ba8312563d:leadership_role:5 - Errol B. De Souza, Ph.D.: Director. Status: current. Independent: true. Since: 2021-01-01. claim_id=alpha:claim:company:dc63c659-5918-479d-8f51-69ba8312563d:leadership_role:6 - Michael F. Higgins: Director. Status: current. Independent: true. Since: 2023-01-01. Committees: Audit (chair); Audit · Chair; Compensation (member); Compensation (member). claim_id=alpha:claim:company:dc63c659-5918-479d-8f51-69ba8312563d:leadership_role:7 - Peter M. Hecht, Ph.D.: Director. Status: current. Independent: false. Since: 2019-01-01. claim_id=alpha:claim:company:dc63c659-5918-479d-8f51-69ba8312563d:leadership_role:8 - Regina M. Graul, Ph.D.: Director. Status: current. Independent: false. Since: 2024-01-01. claim_id=alpha:claim:company:dc63c659-5918-479d-8f51-69ba8312563d:leadership_role:9 - Steven E. Hyman, M.D.: Director. Status: current. Independent: true. Since: 2022-01-01. claim_id=alpha:claim:company:dc63c659-5918-479d-8f51-69ba8312563d:leadership_role:10 ## Committees - Audit (audit). Chair: Michael F. Higgins. Members: Michael F. Higgins (chair, current); Michael F. Higgins (chair, unknown). committee_id=alpha:committee:cyclerion-therapeutics-inc:audit - Audit · Chair; Compensation (audit). Chair: NOT_PUBLISHED. Members: Michael F. Higgins (member, current). committee_id=alpha:committee:cyclerion-therapeutics-inc:audit-chair-compensation - Compensation (compensation). Chair: NOT_PUBLISHED. Members: Michael F. Higgins (member, current); Michael F. Higgins (member, unknown). committee_id=alpha:committee:cyclerion-therapeutics-inc:compensation ## Executive leadership - Regina M. Graul, Ph.D.: President and Chief Executive Officer [CEO]. Status: current. claim_id=alpha:claim:company:dc63c659-5918-479d-8f51-69ba8312563d:leadership_role:11 - Rhonda M. Chicko: Chief Financial Officer [CFO]. Status: current. claim_id=alpha:claim:company:dc63c659-5918-479d-8f51-69ba8312563d:leadership_role:12 ## Governance events - CEO_CHANGED: Regina M. Graul, Ph.D. executive of Cyclerion Therapeutics, Inc., effective 2025-04-29. Effective: 2025-04-29. Detected: 2026-10-09T04:48:32.027887+00:00. event_id=alpha:event:transition:1eev7ue1fej5ng - CFO_CHANGED: Rhonda M. Chicko executive of Cyclerion Therapeutics, Inc., effective 2025-04-29. Effective: 2025-04-29. Detected: 2026-10-09T04:48:32.027887+00:00. event_id=alpha:event:transition:1dkyf7m1fpuq4s - DIRECTOR_APPOINTED: Regina M. Graul, Ph.D. seat on Cyclerion Therapeutics, Inc., effective 2024-01-01. Effective: 2024-01-01. Detected: 2026-10-09T04:48:32.027887+00:00. event_id=alpha:event:transition:16wit6fm1x3qp - DIRECTOR_APPOINTED: Dina Katabi, Ph.D. seat on Cyclerion Therapeutics, Inc., effective 2023-01-01. Effective: 2023-01-01. Detected: 2026-10-09T04:48:32.027887+00:00. event_id=alpha:event:transition:1maovr0aih316 - DIRECTOR_APPOINTED: Michael F. Higgins seat on Cyclerion Therapeutics, Inc., effective 2023-01-01. Effective: 2023-01-01. Detected: 2026-10-09T04:48:32.027887+00:00. event_id=alpha:event:transition:1bt3iqw1m7asyk - COMMITTEE_CREATED: Audit · Chair; Compensation committee of Cyclerion Therapeutics, Inc., effective 2023-01-01. Effective: 2023-01-01. Detected: 2026-10-09T04:48:32.027887+00:00. event_id=alpha:event:transition:1iewdz41ufo52k - COMMITTEE_MEMBER_ADDED: Michael F. Higgins member of Audit · Chair; Compensation, effective 2023-01-01. Effective: 2023-01-01. Detected: 2026-10-09T04:48:32.027887+00:00. event_id=alpha:event:transition:7drph3vqokgn - DIRECTOR_APPOINTED: Steven E. Hyman, M.D. seat on Cyclerion Therapeutics, Inc., effective 2022-01-01. Effective: 2022-01-01. Detected: 2026-10-09T04:48:32.027887+00:00. event_id=alpha:event:transition:ro0x1z1mzawoz - DIRECTOR_APPOINTED: Errol B. De Souza, Ph.D. seat on Cyclerion Therapeutics, Inc., effective 2021-01-01. Effective: 2021-01-01. Detected: 2026-10-09T04:48:32.027887+00:00. event_id=alpha:event:transition:14yi17h1vhoj9f - DIRECTOR_APPOINTED: Peter M. Hecht, Ph.D. seat on Cyclerion Therapeutics, Inc., effective 2019-01-01. Effective: 2019-01-01. Detected: 2026-10-09T04:48:32.027887+00:00. event_id=alpha:event:transition:1lkkg441b27pwe ## Scoped resources - `alpha://company/cyclerion-therapeutics-inc` (contract): https://registry.alpha.ac/api/public/companies/cyclerion-therapeutics-inc?format=record - `alpha://company/cyclerion-therapeutics-inc/identity` (contract): https://registry.alpha.ac/api/public/companies/cyclerion-therapeutics-inc?format=record§ion=identity - `alpha://company/cyclerion-therapeutics-inc/corporate-structure` (contract): https://registry.alpha.ac/api/public/companies/cyclerion-therapeutics-inc?format=record§ion=corporate-structure - `alpha://company/cyclerion-therapeutics-inc/board` (contract): https://registry.alpha.ac/api/public/companies/cyclerion-therapeutics-inc?format=record§ion=board - `alpha://company/cyclerion-therapeutics-inc/committees` (contract): https://registry.alpha.ac/api/public/companies/cyclerion-therapeutics-inc?format=record§ion=committees - `alpha://company/cyclerion-therapeutics-inc/leadership` (contract): https://registry.alpha.ac/api/public/companies/cyclerion-therapeutics-inc?format=record§ion=leadership - `alpha://company/cyclerion-therapeutics-inc/ownership` (contract): https://registry.alpha.ac/api/public/companies/cyclerion-therapeutics-inc?format=record§ion=ownership - `alpha://company/cyclerion-therapeutics-inc/financials` (contract): https://registry.alpha.ac/api/public/companies/cyclerion-therapeutics-inc?format=record§ion=financials - `alpha://company/cyclerion-therapeutics-inc/capital-structure` (contract): https://registry.alpha.ac/api/public/companies/cyclerion-therapeutics-inc?format=record§ion=capital-structure - `alpha://company/cyclerion-therapeutics-inc/compensation` (contract): https://registry.alpha.ac/api/public/companies/cyclerion-therapeutics-inc?format=record§ion=compensation - `alpha://company/cyclerion-therapeutics-inc/governance` (contract): https://registry.alpha.ac/api/public/companies/cyclerion-therapeutics-inc?format=record§ion=governance - `alpha://company/cyclerion-therapeutics-inc/shareholder-governance` (contract): https://registry.alpha.ac/api/public/companies/cyclerion-therapeutics-inc?format=record§ion=shareholder-governance - `alpha://company/cyclerion-therapeutics-inc/audit` (contract): https://registry.alpha.ac/api/public/companies/cyclerion-therapeutics-inc?format=record§ion=audit - `alpha://company/cyclerion-therapeutics-inc/legal` (contract): https://registry.alpha.ac/api/public/companies/cyclerion-therapeutics-inc?format=record§ion=legal - `alpha://company/cyclerion-therapeutics-inc/risk` (contract): https://registry.alpha.ac/api/public/companies/cyclerion-therapeutics-inc?format=record§ion=risk - `alpha://company/cyclerion-therapeutics-inc/cyber` (contract): https://registry.alpha.ac/api/public/companies/cyclerion-therapeutics-inc?format=record§ion=cyber - `alpha://company/cyclerion-therapeutics-inc/ai-governance` (contract): https://registry.alpha.ac/api/public/companies/cyclerion-therapeutics-inc?format=record§ion=ai-governance - `alpha://company/cyclerion-therapeutics-inc/agents` (contract): https://registry.alpha.ac/api/public/companies/cyclerion-therapeutics-inc?format=record§ion=agents - `alpha://company/cyclerion-therapeutics-inc/ecosystem` (contract): https://registry.alpha.ac/api/public/companies/cyclerion-therapeutics-inc?format=record§ion=ecosystem - `alpha://company/cyclerion-therapeutics-inc/events` (contract): https://registry.alpha.ac/api/public/companies/cyclerion-therapeutics-inc?format=record§ion=events - `alpha://company/cyclerion-therapeutics-inc/relationships` (contract): https://registry.alpha.ac/api/public/companies/cyclerion-therapeutics-inc?format=record§ion=relationships - `alpha://company/cyclerion-therapeutics-inc/assessments` (contract): https://registry.alpha.ac/api/public/companies/cyclerion-therapeutics-inc?format=record§ion=assessments - `alpha://company/cyclerion-therapeutics-inc/evidence` (contract): https://registry.alpha.ac/api/public/companies/cyclerion-therapeutics-inc?format=record§ion=evidence ## Role modules - NOT_ASSERTED ## Attention - NO_RECORDS_FOUND ## Committee data - Claim alpha:claim:company:dc63c659-5918-479d-8f51-69ba8312563d:committee_appointment:14: `{"kind":"committee_appointment","original_name":"Audit","category":"audit","role":"chair","person":{"alpha_id":"alpha:person:michael-f-higgins","name":"Michael F. Higgins"},"source_id":"board_seats"}` - Claim alpha:claim:company:dc63c659-5918-479d-8f51-69ba8312563d:committee_appointment:16: `{"kind":"committee_appointment","original_name":"Compensation","category":"compensation","role":"member","person":{"alpha_id":"alpha:person:michael-f-higgins","name":"Michael F. Higgins"},"source_id":"board_seats"}` ## Leadership - Dina Katabi, Ph.D.: Director. Claim: alpha:claim:company:dc63c659-5918-479d-8f51-69ba8312563d:leadership_role:5. Valid from: 2023-01-01. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:35ef1157fdd56119cd2b36a0b0aa99014d68e54fcca8014df96f5410bb60aaf8. - Errol B. De Souza, Ph.D.: Director. Claim: alpha:claim:company:dc63c659-5918-479d-8f51-69ba8312563d:leadership_role:6. Valid from: 2021-01-01. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:35ef1157fdd56119cd2b36a0b0aa99014d68e54fcca8014df96f5410bb60aaf8. - Michael F. Higgins: Director, Audit · Chair; Compensation. Claim: alpha:claim:company:dc63c659-5918-479d-8f51-69ba8312563d:leadership_role:7. Valid from: 2023-01-01. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:35ef1157fdd56119cd2b36a0b0aa99014d68e54fcca8014df96f5410bb60aaf8. - Peter M. Hecht, Ph.D.: Director. Claim: alpha:claim:company:dc63c659-5918-479d-8f51-69ba8312563d:leadership_role:8. Valid from: 2019-01-01. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:35ef1157fdd56119cd2b36a0b0aa99014d68e54fcca8014df96f5410bb60aaf8. - Regina M. Graul, Ph.D.: Director. Claim: alpha:claim:company:dc63c659-5918-479d-8f51-69ba8312563d:leadership_role:9. Valid from: 2024-01-01. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:35ef1157fdd56119cd2b36a0b0aa99014d68e54fcca8014df96f5410bb60aaf8. - Steven E. Hyman, M.D.: Director. Claim: alpha:claim:company:dc63c659-5918-479d-8f51-69ba8312563d:leadership_role:10. Valid from: 2022-01-01. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:35ef1157fdd56119cd2b36a0b0aa99014d68e54fcca8014df96f5410bb60aaf8. - Regina M. Graul, Ph.D.: President and Chief Executive Officer. Claim: alpha:claim:company:dc63c659-5918-479d-8f51-69ba8312563d:leadership_role:11. Valid from: 2025-04-29. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:360214bc2b6424c8de5c957846ff33a71491f59911ccba7256a5a1e95d3d92dd. - Rhonda M. Chicko: Chief Financial Officer. Claim: alpha:claim:company:dc63c659-5918-479d-8f51-69ba8312563d:leadership_role:12. Valid from: 2025-04-29. Valid to: NOT_ASSERTED. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:document:0940532ae5fdfcd902fb3a2eb10fbfe6b63854af36ecf66fbe42dd77ebfaa31b. ## Roles - PUBLISHED ## Governance - NOT_ASSERTED ## Board committees - Audit: Chair Michael F. Higgins; Members Michael F. Higgins (Chair). Claim: alpha:claim:company:dc63c659-5918-479d-8f51-69ba8312563d:committee_record:13. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:aca08fcc2658c809eb8c3c96d6f80f148f2ac7b79c26b282817e6b1c3cbf3df4. - Compensation: Chair not stated; Members Michael F. Higgins. Claim: alpha:claim:company:dc63c659-5918-479d-8f51-69ba8312563d:committee_record:15. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:aca08fcc2658c809eb8c3c96d6f80f148f2ac7b79c26b282817e6b1c3cbf3df4. ## Financials - NOT_ASSERTED ## Workforce - NOT_ASSERTED ## Market and index context - PUBLISHED ## Legal Name - Cyclerion Therapeutics, Inc.. Claim: alpha:claim:company:dc63c659-5918-479d-8f51-69ba8312563d:legal_name:1. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:d654b228a235798d8387a8824742c2fa29eb0d419307835b90a82ecea78af3e8. ## Entity Status - Public listing published. Claim: alpha:claim:company:dc63c659-5918-479d-8f51-69ba8312563d:entity_status:3. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:d654b228a235798d8387a8824742c2fa29eb0d419307835b90a82ecea78af3e8. ## Published Fact - US. Claim: alpha:claim:company:dc63c659-5918-479d-8f51-69ba8312563d:published_fact:4. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:d654b228a235798d8387a8824742c2fa29eb0d419307835b90a82ecea78af3e8. ## Committee Appointment - Michael F. Higgins: chair, Audit. Claim: alpha:claim:company:dc63c659-5918-479d-8f51-69ba8312563d:committee_appointment:14. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:aca08fcc2658c809eb8c3c96d6f80f148f2ac7b79c26b282817e6b1c3cbf3df4. - Michael F. Higgins: member, Compensation. Claim: alpha:claim:company:dc63c659-5918-479d-8f51-69ba8312563d:committee_appointment:16. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:aca08fcc2658c809eb8c3c96d6f80f148f2ac7b79c26b282817e6b1c3cbf3df4. ## Security Listing - CYCN (NASDAQ). Claim: alpha:claim:company:dc63c659-5918-479d-8f51-69ba8312563d:security_listing:17. Publication: PUBLISHED. Verification: source_reported. Assertion: source_reported. Evidence: alpha:projection-evidence:d654b228a235798d8387a8824742c2fa29eb0d419307835b90a82ecea78af3e8. ## Coverage states | Field | Value | | --- | --- | | Identity | PUBLISHED | | Business | PUBLISHED | | Leadership | PUBLISHED | | Board and committees | PUBLISHED | | Governance | NOT_ASSERTED | | Financials | NOT_ASSERTED | | Workforce | NOT_ASSERTED | | Ownership | NOT_ASSERTED | | Ratings | NOT_PUBLISHED | | Market and index context | PUBLISHED | ## Public sources - alpha:projection-evidence:d654b228a235798d8387a8824742c2fa29eb0d419307835b90a82ecea78af3e8: [Alpha canonical company public projection](https://www.alpha.ac/api/public/companies/cyclerion-therapeutics-inc). - alpha:projection-evidence:document:35ef1157fdd56119cd2b36a0b0aa99014d68e54fcca8014df96f5410bb60aaf8: [Cyclerion Therapeutics, Inc. DEF 14A 2025-04-29](https://www.sec.gov/Archives/edgar/data/1755237/000114036125016370/ny20045439x1_def14a.htm). - alpha:projection-evidence:document:360214bc2b6424c8de5c957846ff33a71491f59911ccba7256a5a1e95d3d92dd: [CYCN DEF 14A executive officers](https://www.sec.gov/Archives/edgar/data/1755237/000114036125016370/ny20045439x1_def14a.htm). - alpha:projection-evidence:document:0940532ae5fdfcd902fb3a2eb10fbfe6b63854af36ecf66fbe42dd77ebfaa31b: [CYCN DEF 14A executive officers](https://www.sec.gov/Archives/edgar/data/1755237/000114036125016370/ny20045439x1_def14a.htm). - alpha:projection-evidence:aca08fcc2658c809eb8c3c96d6f80f148f2ac7b79c26b282817e6b1c3cbf3df4: [Audit](https://www.sec.gov/Archives/edgar/data/1755237/000114036125016370/ny20045439x1_def14a.htm). ## Rights | Field | Value | | --- | --- | | public_retrieval | allowed | | agent_retrieval | allowed | | redistribution | not_granted | | model_training | not_granted | | commercial_use | not_specified | | relationship_pathfinding | not_granted | | direct_contact | not_granted | ## Limitations - Absence of a leadership role, committee, or disclosure is not evidence that it does not exist. - Only explicitly published canonical company identity and current confirmed public roles are included. - Absence of a board, committee, executive, listing, or claim is not evidence that it does not exist. - Public retrieval does not grant redistribution, model-training, direct-contact, or relationship-pathfinding rights. - This Company Profile is an identity and evidence record, not an Alpha rating. ## Alternate representations - [Canonical profile](https://registry.alpha.ac/companies/cyclerion-therapeutics-inc) - [Public Markdown](https://registry.alpha.ac/companies/cyclerion-therapeutics-inc.md) - [Public JSON](https://registry.alpha.ac/api/public/companies/cyclerion-therapeutics-inc?format=record) - [JSON-LD](https://registry.alpha.ac/api/public/companies/cyclerion-therapeutics-inc?format=jsonld) - MCP resource: `alpha://companies/cyclerion-therapeutics-inc` at https://mcp.alpha.ac/mcp ## Connected governance records Only explicitly published, rights-cleared records. Missing records do not establish absence, safety, or complete coverage. ## Critical-risk oversight Snapshot as of 2026-10-09T17:11:23.062659+00:00; recorded 2026-10-09T17:11:23.062659+00:00. Every published assignment for this snapshot is listed. Only explicitly reviewed, rights-cleared assignments in effect on the as-of date, in the company's own wording. An assignment shows where oversight is placed, not whether it is effective. Missing records do not establish absence.